Ecotoxicology

History of the Group

This group of research was created in 2011. It includes some members of the former LICAS Group- Faculty of Exact and Natural Sciences- UNMDP directed by Dr. Víctor J. Moreno and Dra. Julia E. A. de Moreno. Our group is interested on aquatic ecotoxicology, focusing on effects at biochemical and genetic level in aquatic non target organisms exposed to organic pollutants, like current- use pesticides.

Lines of Research

Monitoring of aquatic pollution
Biochemical biomarkers (detoxication and antioxidant enzymes, endogenous metabolites)
Biomarkers of genotoxicity (cytogenetic and molecular)
Molecular biomarkers (isoenzyme expression)

Director
Dra. Menone Mirta Luján CV-SIGEVA	Researcher CONICET Professor Teaching assistant	Publications 3418672 Menone 1 apa 50 date desc 1699 Lombardero, L. R., Truchet, D. M., Medici, S. K., Mendieta, J. R., Pérez, D. J., & Menone, M. L. (2024). Assessment of the Potential Phytotoxicity of Chlorpyrifos in the Wetland Macrophyte Bidens laevis (L.). Bulletin of Environmental Contamination and Toxicology, 113(4), 45. https://doi.org/10.1007/s00128-024-03957-z Villagran, D. M., Lombardero, L. R., Crupkin, A. C., Mendieta, J. R., Medici, S. K., Lavarello, F., Simoniello, M. F., & Menone, M. L. (2023). Can the herbicide dicamba produce oxidative stress in the native South American fish Jenynsia lineata at environmentally relevant concentrations? Bulletin of Environmental Contamination and Toxicology, 111(3), 41. https://doi.org/10.1007/s00128-023-03796-4 Bertrand, L., Iturburu, F. G., Valdés, M. E., Menone, M. L., & Amé, M. V. (2023). Risk evaluation and prioritization of contaminants of emerging concern and other organic micropollutants in two river basins of central Argentina. Science of The Total Environment, 878, 163029. https://doi.org/10.1016/j.scitotenv.2023.163029 Menone, M. L., & Pérez, D. J. (2023). Biomarkers in Aquatic Macrophytes: Traditional and Novel Approaches for Monitoring Responses to Exposure to Pollutants. In M. L. Menone & C. Metcalfe (Eds.), The Ecotoxicology of Aquatic Macrophytes (pp. 11–52). Springer International Publishing. https://doi.org/10.1007/978-3-031-27833-4_2 Menone, M. L., Humeniuk, B. W., & Metcalfe, C. D. (2023). The Ecotoxicology of Aquatic Macrophytes: An Overview. In The Ecotoxicology of Aquatic Macrophytes (pp. 1–10). Springer International Publishing. https://doi.org/10.1007/978-3-031-27833-4_1 Menone, M. L., Iturburu, F. G., Demetrio, P. M., Venturino, A., Pedrozo, F. L., Temporetti, P. F., Rodríguez, A., Amé, M. V., Quaini, K. P., & Collins, P. (2022). Calidad del agua y niveles guía para la protección de la biodiversidad acuática. Interacción entre ciencia y gestión. Ecología Austral, 32, 245–257. http://ojs.ecologiaaustral.com.ar/index.php/Ecologia_Austral/article/view/1722 Pérez, D. J., Okada, E., Iturburu, F. G., De Gerónimo, E., Cantón, G., Aparicio, V. C., Costa, J. L., & Menone, M. L. (2021). Monensin occurrence in surface water and its impact on aquatic biota in a stream of the southeast Pampas, Argentina. Environmental Science and Pollution Research, 28(7), 8530–8538. https://doi.org/10.1007/s11356-020-11009-2 Crupkin, A. C., Fulvi, A. B., Iturburu, F. G., Medici, S., Mendieta, J., Panzeri, A. M., & Menone, M. L. (2021). Evaluation of hematological parameters, oxidative stress and DNA damage in the cichlid Australoheros facetus exposed to the fungicide azoxystrobin. Ecotoxicology and Environmental Safety, 207, 111286. https://doi.org/10.1016/j.ecoenv.2020.111286 Corcoran, S., Metcalfe, C. D., Sultana, T., Amé, M. V., & Menone, M. L. (2020). Pesticides in surface waters in Argentina monitored using polar organic chemical integrative samplers. Bulletin of Environmental Contamination and Toxicology, 104, 21–26. https://doi.org/10.1007/s00128-019-02758-z Negro, C. L., Iturburu, F. G., Mendieta, J., Menone, M. L., & Collins, P. (2019). Are oxidative stress biomarkers sensitive to environmental concentrations of chlorpyrifos exposed to the freshwater crab, Zilchiopsis collastinensis (Decapoda; Trichodactylidae)? Bulletin of Environmental Contamination and Toxicology, 103(3), 405–410. https://doi.org/10.1007/s00128-019-02643-9 Moreyra, L. D., Garanzini, D. S., Medici, S., & Menone, M. L. (2019). Evaluation of growth, photosynthetic pigments and genotoxicity in the wetland macrophyte Bidens laevis exposed to tebuconazole. Bulletin of Environmental Contamination and Toxicology, 102(3), 353–357. https://doi.org/10.1007/s00128-019-02539-8 Garanzini, D. S., Medici, S., Moreyra, L. D., & Menone, M. L. (2019). Acute exposure to a commercial formulation of Azoxystrobin alters antioxidant enzymes and elicit damage in the aquatic macrophyte Myriophyllum quitense. Physiology and Molecular Biology of Plants, 25(1), 135–143. https://doi.org/10.1007/s12298-018-0603-7 Iturburu, F. G., Bertrand, L., Mendieta, J. R., Amé, M. V., & Menone, M. L. (2018). An integrated biomarker response study explains more than the sum of the parts: Oxidative stress in the fish Australoheros facetus exposed to imidacloprid. Ecological Indicators, 93, 351–357. https://doi.org/10.1016/j.ecolind.2018.05.019 Crupkin, A. C., Iturburu, F. G., Crupkin, M., & Menone, M. L. (2018). Myofibrilar functional dysregulation in fish: A new biomarker of damage to pesticides. Ecotoxicology and Environmental Safety, 158, 44–49. https://doi.org/10.1016/j.ecoenv.2018.03.096 Iturburu, F. G., Simoniello, M. F., Medici, S., Panzeri, A. M., & Menone, M. L. (2018). Imidacloprid causes DNA damage in fish: clastogenesis as a mechanism of genotoxicity. Bulletin of Environmental Contamination and Toxicology, 100(6), 760–764. https://doi.org/10.1007/s00128-018-2338-0 Lukaszewicz, G., Amé, M. V., & Menone, M. L. (2018). Selection of reference genes for reverse transcription-qPCR analysis in the biomonitor macrophyte <Emphasis Type="Italic">Bidens laevis</Emphasis> L. Physiology and Molecular Biology of Plants, 24(5), 781–792. https://doi.org/10.1007/s12298-018-0534-3 Pérez, D. J., Okada, E., Menone, M. L., & Costa, J. L. (2017). Can an aquatic macrophyte bioaccumulate glyphosate? Development of a new method of glyphosate extraction in Ludwigia peploides and watershed scale validation. Chemosphere, 185, 975–982. https://doi.org/10.1016/j.chemosphere.2017.07.093 Iturburu, F. G., Zömisch, M., Panzeri, P., Ana María, Crupkin, C., Andrea Carina, Contardo-Jara, V., Pflugmacher, S., & Menone, M. L. (2017). Uptake, distribution in different tissues, and genotoxicity of imidacloprid in the freshwater fish Australoheros facetus. Environmental Toxicology and Chemistry, 36(3), 699–708. https://doi.org/10.1002/etc.3574 Menone, M. L., Pérez, D. J., Lukaszewicz, G., & Camadro, E. L. (2015). Identificación de hidrófitas dulceacuícolas para estudios de genotoxicidad de contaminantes acuáticos. Journal of Basic and Applied Genetics, 26(1), 9–17. http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S1852-62332015000100002 Salvio, C., Manetti, P. L., Clemente, N. L., Menone, M. L., & López, A. N. (2015). Toxicidad subletal de clorpirifos sobre Octolasion cyaneum (Annelida: Oligochaeta, Lumbricidae). Agriscientia, 32(2), 131–138. http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S1668-298X2015000200006 Garanzini, D. S., & Menone, M. L. (2015). Azoxystrobin causes oxidative stress and DNA damage in the aquatic macrophyte Myriophyllum quitense. Bulletin of Environmental Contamination and Toxicology, 94(2), 146–151. http://link.springer.com/article/10.1007/s00128-014-1428-x Pérez, D. J., Lukaszewicz, G., Menone, M. L., Amé, M. V., & Camadro, E. L. (2014). Genetic and biochemical biomarkers in the macrophyte Bidens laevis L. exposed to a commercial formulation of endosulfan. Environmental Toxicology, 29(9), 1063–1071. http://onlinelibrary.wiley.com/doi/10.1002/tox.21836/full Crupkin, A. C., Carriquiriborde, P., Mendieta, J., Panzeri, A. M., Ballesteros, M. L., Miglioranza, K. S. B., & Menone, M. L. (2013). Oxidative stress and genotoxicity in the South American cichlid, Australoheros facetus, after short-term sublethal exposure to endosulfan. Pesticide Biochemistry and Physiology, 105(2), 102–110. http://www.sciencedirect.com/science/article/pii/S0048357512001861 Crupkin, A. C., & Menone, M. L. (2013). Changes in the activities of glutathione-S-transferases, glutathione reductase and catalase after exposure to different concentrations of cadmium in Australoheros facetus (Cichlidae, Pisces). Ecotoxicology and Environmental Contamination, 8(1), 21–25. http://siaiap32.univali.br/seer/index.php/eec/article/view/3152

Co-Director
Dra. Crupkin Andrea Carina	Researcher CIC Professor Teaching assistant	Publications 3418672 CRUPKIN 1 apa 50 date desc 1699 Villagran, D. M., Lombardero, L. R., Crupkin, A. C., Mendieta, J. R., Medici, S. K., Lavarello, F., Simoniello, M. F., & Menone, M. L. (2023). Can the herbicide dicamba produce oxidative stress in the native South American fish Jenynsia lineata at environmentally relevant concentrations? Bulletin of Environmental Contamination and Toxicology, 111(3), 41. https://doi.org/10.1007/s00128-023-03796-4 Crupkin, A. C., Fulvi, A. B., Iturburu, F. G., Medici, S., Mendieta, J., Panzeri, A. M., & Menone, M. L. (2021). Evaluation of hematological parameters, oxidative stress and DNA damage in the cichlid Australoheros facetus exposed to the fungicide azoxystrobin. Ecotoxicology and Environmental Safety, 207, 111286. https://doi.org/10.1016/j.ecoenv.2020.111286 Crupkin, A. C., Iturburu, F. G., Crupkin, M., & Menone, M. L. (2018). Myofibrilar functional dysregulation in fish: A new biomarker of damage to pesticides. Ecotoxicology and Environmental Safety, 158, 44–49. https://doi.org/10.1016/j.ecoenv.2018.03.096 Iturburu, F. G., Zömisch, M., Panzeri, P., Ana María, Crupkin, C., Andrea Carina, Contardo-Jara, V., Pflugmacher, S., & Menone, M. L. (2017). Uptake, distribution in different tissues, and genotoxicity of imidacloprid in the freshwater fish Australoheros facetus. Environmental Toxicology and Chemistry, 36(3), 699–708. https://doi.org/10.1002/etc.3574 Crupkin, A. C., Carriquiriborde, P., Mendieta, J., Panzeri, A. M., Ballesteros, M. L., Miglioranza, K. S. B., & Menone, M. L. (2013). Oxidative stress and genotoxicity in the South American cichlid, Australoheros facetus, after short-term sublethal exposure to endosulfan. Pesticide Biochemistry and Physiology, 105(2), 102–110. http://www.sciencedirect.com/science/article/pii/S0048357512001861 Crupkin, A. C., & Menone, M. L. (2013). Changes in the activities of glutathione-S-transferases, glutathione reductase and catalase after exposure to different concentrations of cadmium in Australoheros facetus (Cichlidae, Pisces). Ecotoxicology and Environmental Contamination, 8(1), 21–25. http://siaiap32.univali.br/seer/index.php/eec/article/view/3152

Researchers
Dr. Iturburu Fernando Gastón CV-SIGEVA	Researcher CONICET Teaching assistant	Publications 3418672 Iturburu 1 apa 50 date desc 1699 Bertrand, L., Iturburu, F. G., Valdés, M. E., Menone, M. L., & Amé, M. V. (2023). Risk evaluation and prioritization of contaminants of emerging concern and other organic micropollutants in two river basins of central Argentina. Science of The Total Environment, 878, 163029. https://doi.org/10.1016/j.scitotenv.2023.163029 Menone, M. L., Iturburu, F. G., Demetrio, P. M., Venturino, A., Pedrozo, F. L., Temporetti, P. F., Rodríguez, A., Amé, M. V., Quaini, K. P., & Collins, P. (2022). Calidad del agua y niveles guía para la protección de la biodiversidad acuática. Interacción entre ciencia y gestión. Ecología Austral, 32, 245–257. http://ojs.ecologiaaustral.com.ar/index.php/Ecologia_Austral/article/view/1722 Pérez, D. J., Okada, E., Iturburu, F. G., De Gerónimo, E., Cantón, G., Aparicio, V. C., Costa, J. L., & Menone, M. L. (2021). Monensin occurrence in surface water and its impact on aquatic biota in a stream of the southeast Pampas, Argentina. Environmental Science and Pollution Research, 28(7), 8530–8538. https://doi.org/10.1007/s11356-020-11009-2 Crupkin, A. C., Fulvi, A. B., Iturburu, F. G., Medici, S., Mendieta, J., Panzeri, A. M., & Menone, M. L. (2021). Evaluation of hematological parameters, oxidative stress and DNA damage in the cichlid Australoheros facetus exposed to the fungicide azoxystrobin. Ecotoxicology and Environmental Safety, 207, 111286. https://doi.org/10.1016/j.ecoenv.2020.111286 Negro, C. L., Iturburu, F. G., Mendieta, J., Menone, M. L., & Collins, P. (2019). Are oxidative stress biomarkers sensitive to environmental concentrations of chlorpyrifos exposed to the freshwater crab, Zilchiopsis collastinensis (Decapoda; Trichodactylidae)? Bulletin of Environmental Contamination and Toxicology, 103(3), 405–410. https://doi.org/10.1007/s00128-019-02643-9 Iturburu, F. G., Bertrand, L., Mendieta, J. R., Amé, M. V., & Menone, M. L. (2018). An integrated biomarker response study explains more than the sum of the parts: Oxidative stress in the fish Australoheros facetus exposed to imidacloprid. Ecological Indicators, 93, 351–357. https://doi.org/10.1016/j.ecolind.2018.05.019 Crupkin, A. C., Iturburu, F. G., Crupkin, M., & Menone, M. L. (2018). Myofibrilar functional dysregulation in fish: A new biomarker of damage to pesticides. Ecotoxicology and Environmental Safety, 158, 44–49. https://doi.org/10.1016/j.ecoenv.2018.03.096 Iturburu, F. G., Simoniello, M. F., Medici, S., Panzeri, A. M., & Menone, M. L. (2018). Imidacloprid causes DNA damage in fish: clastogenesis as a mechanism of genotoxicity. Bulletin of Environmental Contamination and Toxicology, 100(6), 760–764. https://doi.org/10.1007/s00128-018-2338-0 Iturburu, F. G., Zömisch, M., Panzeri, P., Ana María, Crupkin, C., Andrea Carina, Contardo-Jara, V., Pflugmacher, S., & Menone, M. L. (2017). Uptake, distribution in different tissues, and genotoxicity of imidacloprid in the freshwater fish Australoheros facetus. Environmental Toxicology and Chemistry, 36(3), 699–708. https://doi.org/10.1002/etc.3574

Graduate Students
Dra. Truchet Daniela CV-SIGEVA	Graduate fellowship	Publications 3418672 Truchet 1 apa 50 date desc 1699 Lombardero, L. R., Truchet, D. M., Medici, S. K., Mendieta, J. R., Pérez, D. J., & Menone, M. L. (2024). Assessment of the Potential Phytotoxicity of Chlorpyrifos in the Wetland Macrophyte Bidens laevis (L.). Bulletin of Environmental Contamination and Toxicology, 113(4), 45. https://doi.org/10.1007/s00128-024-03957-z Truchet, D. M., Noceti, B. M., Villagran, D. M., & Truchet, R. M. (2022). Alternative Conservation Paradigms and Ecological Knowledge of Small-Scale Artisanal Fishers in a Changing Marine Scenario in Argentina. Human Ecology, 50, 209–225. https://doi.org/10.1007/s10745-022-00309-5
Dra. Villagran Diana Mariel CV-SIGEVA	Graduate fellowship	Publications 3418672 VILLAGRAN 1 apa 50 date desc 1699 Villagran, D. M., Lombardero, L. R., Crupkin, A. C., Mendieta, J. R., Medici, S. K., Lavarello, F., Simoniello, M. F., & Menone, M. L. (2023). Can the herbicide dicamba produce oxidative stress in the native South American fish Jenynsia lineata at environmentally relevant concentrations? Bulletin of Environmental Contamination and Toxicology, 111(3), 41. https://doi.org/10.1007/s00128-023-03796-4 Frayssinet, C., Osterrieth, M. L., Fernández Honaine, M., Marcovecchio, J. E., La Colla, N., & Villagran, D. (2023). Relationship between silica and silicophytoliths with heavy metals in a wheat (Triticum aestivum) planted with silicon fertilization. Sustainable Water Resources Management, 9(3), 84. https://doi.org/10.1007/s40899-023-00861-y Truchet, D. M., Noceti, B. M., Villagran, D. M., & Truchet, R. M. (2022). Alternative Conservation Paradigms and Ecological Knowledge of Small-Scale Artisanal Fishers in a Changing Marine Scenario in Argentina. Human Ecology, 50, 209–225. https://doi.org/10.1007/s10745-022-00309-5
Nascimento Pereira Thaís	Graduate fellowship	Publications 3418672 Nascimento Pereira 1 apa 50 date desc 1699
Ojeda Rossi Gastón Ezequiel	Graduate fellowship Teaching assistant	Publications 3418672 Ojeda Rossi 1 apa 50 date desc 1699