Physiology of Aquatic Organisms and Applied Biotechnology (OCA 1215/12; 1406/17; 1412/17)  is a research group recently formed and devoted to the study of a variety of aquatic animals – as crustaceans, mollusks and fish- with focus in their nutrition and immunology. This approach allows us to understand the biochemical and physiological processes that modulate their adaptations to a particular environment. The knowledge about biochemical mechanisms related to the immunity and digestive physiology let us to link species to their habitat according to their physioecological features. Over the last years, it has been demonstrated that studying the immunological processes associated to the biochemical physiology can help to determine organisms overall health status. However, most research efforts have been directed to study separately the physiology and immunology; as consequence, little is known about the linkage between metabolic and immunological processes. Therefore, to study the immunological condition of an organism an integrative analysis is required. Some recent nutritional studies emphasize that feed not only has to fill nutritional needs, but also should modulate several organism functions and must play a beneficial role during illnesses. In aquaculture industry research efforts have been directed to understand digestive physiology, becoming in Usually, fish meal is the main ingredient employed in feed formulations, in Argentina this meal is prepared from fish processing wastes and/or non-target organisms that were captured. One of the main goals for food technologists is to promote the use of fisheries wastes through mild methods that allow raw material recovery and, thus, keep their nutritional components increasing their added value. The growing development in science and technology opens new opportunities to improve the country productivity. In the last years, the professional staff of this research group studied and tuned up several techniques related to the study of enzyme activity in a variety of species (Fernández Gimenez, 2013; Fernández Gimenez et al., 2009, 2014). In this sense, the main goal of this group is to re-evaluate fishery wastes through the study of the digestive physiology of organisms comprising these sub-exploited resources. Moreover, we encourage the application of our cumulative knowledge about enzymes in the biotechnological field in order to improve national food industry and aquaculture. We offer an alternative use of fishery wastes, reducing negative environmental impacts and promoting environmental sustainability.

Director    
Dra. Fernández Giménez Analía
Researcher CONICET
Professor
Fernández-Gimenez, A. V. (2019). Properties and Some New Applications of Enzymes from Wastes of the Shrimp Pleoticus muelleri (Decapoda, Penaeoidea). Journal of Shellfish Research, 38(3), 635–642. https://doi.org/10.2983/035.038.0315
Rodriguez, Y. E., Sacristán, H. J., Laitano, M. V., López‐Greco, L. S., & Fernández‐Gimenez, A. V. (2019). From fish-processing waste to feed additives for crayfish. Journal of the World Aquaculture Society, 50(5), 954–968. https://doi.org/10.1111/jwas.12585
Laitano, M. V., Díaz-Jaramillo, M., Rodriguez, Y. E., Ducós, E., Panarello, H. O., & Fernández-Gimenez, A. V. (2018). Linking stable isotopes and biochemical responses in Balanus glandula under sewage influence. Marine Pollution Bulletin, 127, 505–511. https://doi.org/10.1016/j.marpolbul.2017.12.036
Rodriguez, Y. E., Laitano, M. V., Pereira, N. A., López-Zavala, A. A., Haran, N. S., & Fernández-Gimenez, A. V. (2018). Exogenous enzymes in aquaculture: Alginate and alginate-bentonite microcapsules for the intestinal delivery of shrimp proteases to Nile tilapia. Aquaculture, 490, 35–43. https://doi.org/10.1016/j.aquaculture.2018.02.022
García, C. F., Pedrini, N., Sánchez-Paz, A., Reyna-Blanco, C. S., Lavarias, S., Muhlia-Almazán, A., Fernández-Giménez, A., Laino, A., de-la-Re-Vega, E., Lukaszewicz, G., López-Zavala, A. A., Brieba, L. G., Criscitello, M. F., Carrasco-Miranda, J. S., García-Orozco, K. D., Ochoa-Leyva, A., Rudiño-Piñera, E., Sanchez-Flores, A., & Sotelo-Mundo, R. R. (2018). De novo assembly and transcriptome characterization of the freshwater prawn Palaemonetes argentinus: Implications for a detoxification response. Marine Genomics, 37, 74–81. https://doi.org/10.1016/j.margen.2017.08.009
Rodriguez, Y. E., Pereira, N. A., Haran, N. S., Mallo, J. C., & Fernández‐Gimenez, A. V. (2017). A new approach to fishery waste revalorization to enhance Nile tilapia (Oreochromis niloticus) digestion process. Aquaculture Nutrition, 23(6), 1351–1361. https://doi.org/10.1111/anu.12510
Sacristán, H. J., Rodriguez, Y. E., Pereira, N. D. los A., Greco, L. S. L., Lovrich, G. A., & Fernandez-Gimenez, A. V. (2017). Energy reserves mobilization: Strategies of three decapod species. PLOS ONE, 12(9), e0184060. https://doi.org/10.1371/journal.pone.0184060
Pereira, N. de los A., & Fernández‐Gimenez, A. V. (2017). Exogenous enzymes in dairy technology: acidic proteases from processing discards of shrimp Pleoticus muelleri and their use as milk-clotting enzymes for cheese manufacture. International Journal of Food Science & Technology, 52(2), 341–347. https://doi.org/10.1111/ijfs.13285
Fernández-Gimenez, A. V., Pereira, N. de los Á., & Sarasa, M. V. (2016). Liposoluble vitamins in crustacean feed: metabolic and histological responses. Indian Journal of Experimental Biology, 54, 297–308. http://nopr.niscair.res.in/handle/123456789/34152
Laitano, M. V., & Fernández-Gimenez, A. V. (2016). Are mussels always the best bioindicators? Comparative study on biochemical responses of three marine invertebrate species to chronic port pollution. Bulletin of Environmental Contamination and Toxicology, 97(1), 50–55. http://link.springer.com/article/10.1007/s00128-016-1839-y
Sacristán, H. J., Fernández-Gimenez, A. V., Chaulet, A., Tadic, F., Marcelo, L., Fenucci, J., & López Greco, L. S. (2015). Effect of different diets on digestive enzyme activities, in vitro digestibility, and midgut gland structure in juvenile crayfish, Cherax quadricarinatus. Acta Zoologica. http://onlinelibrary.wiley.com/doi/10.1111/azo.12134/pdf
Fernandez-Gimenez, A. V., Haran, N. S., Pereira, N. A., & Acuña, F. H. (2014). First report of phenoloxidase and peroxidase activities in two intertidal sea anemone species of Argentina. Invertebrate Survival Journal, 11, 192–196.
Lancia, J. P., Fernández-Gimenez, A. V., Bas, C., & Spivak, E. (2012). Adaptive differences in digestive enzyme activity in the crab Neohelice granulata in relation to sex and habitat. Journal of Crustacean Biology, 32(6), 940–948. http://booksandjournals.brillonline.com/content/journals/10.1163/1937240x-00002090
Rodriguez, Y. E., Pereira, N. A., Laitano, M. V., Moreno, P., & Fernández‐Gimenez, A. V. (n.d.). Exogenous proteases from seafood processing waste as functional additives in rainbow trout aquaculture. Aquaculture Research. https://doi.org/https://doi.org/10.1111/are.15272
Pereira, N. de L. Á., Fangio, M. F., Rodriguez, Y. E., Bonadero, M. C., Harán, N. S., & Fernández‐Gimenez, A. V. (n.d.). Characterization of liquid protein hydrolysates shrimp industry waste: analysis of antioxidant and microbiological activity, and shelf life of final product. Journal of Food Processing and Preservation. https://doi.org/https://doi.org/10.1111/jfpp.15526
Researchers    
Dra. Del Valle Juana Cristina
Researcher UNMDP
Professor
Dra. Pereira Nair De Los Ángeles
Researcher CONICET
Rodriguez, Y. E., Laitano, M. V., Pereira, N. A., López-Zavala, A. A., Haran, N. S., & Fernández-Gimenez, A. V. (2018). Exogenous enzymes in aquaculture: Alginate and alginate-bentonite microcapsules for the intestinal delivery of shrimp proteases to Nile tilapia. Aquaculture, 490, 35–43. https://doi.org/10.1016/j.aquaculture.2018.02.022
Rodriguez, Y. E., Pereira, N. A., Haran, N. S., Mallo, J. C., & Fernández‐Gimenez, A. V. (2017). A new approach to fishery waste revalorization to enhance Nile tilapia (Oreochromis niloticus) digestion process. Aquaculture Nutrition, 23(6), 1351–1361. https://doi.org/10.1111/anu.12510
Sacristán, H. J., Rodriguez, Y. E., Pereira, N. D. los A., Greco, L. S. L., Lovrich, G. A., & Fernandez-Gimenez, A. V. (2017). Energy reserves mobilization: Strategies of three decapod species. PLOS ONE, 12(9), e0184060. https://doi.org/10.1371/journal.pone.0184060
Pereira, N. de los A., & Fernández‐Gimenez, A. V. (2017). Exogenous enzymes in dairy technology: acidic proteases from processing discards of shrimp Pleoticus muelleri and their use as milk-clotting enzymes for cheese manufacture. International Journal of Food Science & Technology, 52(2), 341–347. https://doi.org/10.1111/ijfs.13285
Braicovich, P. E., Pantoja, C., Pereira, A. N., Luque, J. L., & Timi, J. T. (2017). Parasites of the Brazilian flathead Percophis brasiliensis reflect West Atlantic biogeographic regions. Parasitology, 144(2), 169–178.
Fernández-Gimenez, A. V., Pereira, N. de los Á., & Sarasa, M. V. (2016). Liposoluble vitamins in crustacean feed: metabolic and histological responses. Indian Journal of Experimental Biology, 54, 297–308. http://nopr.niscair.res.in/handle/123456789/34152
Alarcos, A. J., Pereira, A. N., Taborda, N. L., Luque, J. L., & Timi, J. T. (2016). Parasitological evidence of stocks of Paralichthys isosceles (Pleuronectiformes: Paralichthyidae) at small and large geographical scales in South American Atlantic coasts. Fisheries Research, 173, 221–228. http://www.sciencedirect.com/science/article/pii/S0165783615300278
Vieira, F. M., Pereira, Felipe. B., Pantoja, C., Soares, I. A., Pereira, A. N., Timi, J. T., Scholz, T., & Luque, J. L. (2015). A survey of nematodes of the genus Cucullanus Müller, 1777 (Nematoda, Seuratoidea) parasitic in marine fishes off Brazil, including description of three new species. Zootaxa, 4039(2), 289–311.
Fernandez-Gimenez, A. V., Haran, N. S., Pereira, N. A., & Acuña, F. H. (2014). First report of phenoloxidase and peroxidase activities in two intertidal sea anemone species of Argentina. Invertebrate Survival Journal, 11, 192–196.
Pereira, A. N., Pantoja, C., Luque, J. L., & Timi, J. T. (2014). Parasites of Urophycis brasiliensis (Gadiformes: Phycidae) as indicators of marine ecoregions in coastal areas of the South American Atlantic. Parasitology Research, 113(11), 4281–4292.
Pereira, F. B., Pereira, A. de N., Timi, J. T., & Luque, J. L. (2013). Pseudascarophis brasiliensis sp. nov.(Nematoda: Cystidicolidae). Memórias Do Instituto Oswaldo Cruz, 108(4), 476–480.
Pereira, A. N., Timi, J. T., Vieira, F. M., & Luque, J. L. (2012). A new species of Neoascarophis (Nematoda: Cystidicolidae) parasitic in Mullus argentinae (Perciformes: Mullidae) from the Atlantic coast of South America. Folia Parasitologica, 59(1), 64.
Rodriguez, Y. E., Pereira, N. A., Laitano, M. V., Moreno, P., & Fernández‐Gimenez, A. V. (n.d.). Exogenous proteases from seafood processing waste as functional additives in rainbow trout aquaculture. Aquaculture Research. https://doi.org/https://doi.org/10.1111/are.15272
Pereira, N. de L. Á., Fangio, M. F., Rodriguez, Y. E., Bonadero, M. C., Harán, N. S., & Fernández‐Gimenez, A. V. (n.d.). Characterization of liquid protein hydrolysates shrimp industry waste: analysis of antioxidant and microbiological activity, and shelf life of final product. Journal of Food Processing and Preservation. https://doi.org/https://doi.org/10.1111/jfpp.15526
Dra. Laitano María Victoria
Researcher CONICET
Teaching Assistant
Rodriguez, Y. E., Sacristán, H. J., Laitano, M. V., López‐Greco, L. S., & Fernández‐Gimenez, A. V. (2019). From fish-processing waste to feed additives for crayfish. Journal of the World Aquaculture Society, 50(5), 954–968. https://doi.org/10.1111/jwas.12585
Díaz-Jaramillo, M., Laitano, M. V., Gonzalez, M., & Miglioranza, K. S. B. (2018). Spatio-temporal trends and body size differences of OCPs and PCBs in Laeonereis culveri (Polychaeta: Nereididae) from Southwest Atlantic estuaries. Marine Pollution Bulletin, 136, 107–113. https://doi.org/10.1016/j.marpolbul.2018.09.008
Laitano, M. V., Díaz-Jaramillo, M., Rodriguez, Y. E., Ducós, E., Panarello, H. O., & Fernández-Gimenez, A. V. (2018). Linking stable isotopes and biochemical responses in Balanus glandula under sewage influence. Marine Pollution Bulletin, 127, 505–511. https://doi.org/10.1016/j.marpolbul.2017.12.036
Rodriguez, Y. E., Laitano, M. V., Pereira, N. A., López-Zavala, A. A., Haran, N. S., & Fernández-Gimenez, A. V. (2018). Exogenous enzymes in aquaculture: Alginate and alginate-bentonite microcapsules for the intestinal delivery of shrimp proteases to Nile tilapia. Aquaculture, 490, 35–43. https://doi.org/10.1016/j.aquaculture.2018.02.022
Laitano, M. V., & Fernández-Gimenez, A. V. (2016). Are mussels always the best bioindicators? Comparative study on biochemical responses of three marine invertebrate species to chronic port pollution. Bulletin of Environmental Contamination and Toxicology, 97(1), 50–55. http://link.springer.com/article/10.1007/s00128-016-1839-y
Laitano, M. V., Barni, M. S., Costa, P. G., Cledón, M., Fillmann, G., Miglioranza, K. S. B., & Panarello, H. O. (2016). Different carbon sources affect PCB accumulation by marine bivalves. Marine Environmental Research, 113, 62–69. http://www.sciencedirect.com/science/article/pii/S0141113615300702
Laitano, M. V., Castro, Í. B., Costa, P. G., Fillmann, G., & Cledón, M. (2015). Butyltin and PAH contamination of Mar del Plata port (Argentina) sediments and their influence on adjacent coastal regions. Bulletin of Environmental Contamination and Toxicology, 95(4), 513–520. http://link.springer.com/article/10.1007/s00128-015-1637-y
Nuñez, J. D., Laitano, M. V., Meretta, P. E., & Ocampo, E. H. (2014). Burrowing behavior of an infaunal clam species after siphon nipping. Journal of Experimental Marine Biology and Ecology, 459, 45–50.
Laitano, M. V., Nuñez, J. D., & Cledón, M. (2013). Shell alterations in the limpet Bostrycapulus odites: A bioindicator of harbour pollution and mine residuals. Ecological Indicators, 34, 345–351. http://www.sciencedirect.com/science/article/pii/S1470160X13002276
Laitano, M. V., Farías, N. E., & Cledón, M. (2013). Prey preference of the stone crab Platyxanthus crenulatus (Decapoda: Platyxanthidae) in laboratory conditions. Nauplius, 21(1), 17–23. http://www.scielo.br/scielo.php?pid=S0104-64972013000100003&script=sci_arttext&tlng=pt
Rodriguez, Y. E., Pereira, N. A., Laitano, M. V., Moreno, P., & Fernández‐Gimenez, A. V. (n.d.). Exogenous proteases from seafood processing waste as functional additives in rainbow trout aquaculture. Aquaculture Research. https://doi.org/https://doi.org/10.1111/are.15272
Dra. Rodríguez Yamila Eliana
Researcher CONICET
Rodriguez, Y. E., Sacristán, H. J., Laitano, M. V., López‐Greco, L. S., & Fernández‐Gimenez, A. V. (2019). From fish-processing waste to feed additives for crayfish. Journal of the World Aquaculture Society, 50(5), 954–968. https://doi.org/10.1111/jwas.12585
Laitano, M. V., Díaz-Jaramillo, M., Rodriguez, Y. E., Ducós, E., Panarello, H. O., & Fernández-Gimenez, A. V. (2018). Linking stable isotopes and biochemical responses in Balanus glandula under sewage influence. Marine Pollution Bulletin, 127, 505–511. https://doi.org/10.1016/j.marpolbul.2017.12.036
Rodriguez, Y. E., Laitano, M. V., Pereira, N. A., López-Zavala, A. A., Haran, N. S., & Fernández-Gimenez, A. V. (2018). Exogenous enzymes in aquaculture: Alginate and alginate-bentonite microcapsules for the intestinal delivery of shrimp proteases to Nile tilapia. Aquaculture, 490, 35–43. https://doi.org/10.1016/j.aquaculture.2018.02.022
Rodriguez, Y. E., Pereira, N. A., Haran, N. S., Mallo, J. C., & Fernández‐Gimenez, A. V. (2017). A new approach to fishery waste revalorization to enhance Nile tilapia (Oreochromis niloticus) digestion process. Aquaculture Nutrition, 23(6), 1351–1361. https://doi.org/10.1111/anu.12510
Sacristán, H. J., Rodriguez, Y. E., Pereira, N. D. los A., Greco, L. S. L., Lovrich, G. A., & Fernandez-Gimenez, A. V. (2017). Energy reserves mobilization: Strategies of three decapod species. PLOS ONE, 12(9), e0184060. https://doi.org/10.1371/journal.pone.0184060
Rodriguez, Y. E., Pereira, N. A., Laitano, M. V., Moreno, P., & Fernández‐Gimenez, A. V. (n.d.). Exogenous proteases from seafood processing waste as functional additives in rainbow trout aquaculture. Aquaculture Research. https://doi.org/https://doi.org/10.1111/are.15272
Pereira, N. de L. Á., Fangio, M. F., Rodriguez, Y. E., Bonadero, M. C., Harán, N. S., & Fernández‐Gimenez, A. V. (n.d.). Characterization of liquid protein hydrolysates shrimp industry waste: analysis of antioxidant and microbiological activity, and shelf life of final product. Journal of Food Processing and Preservation. https://doi.org/https://doi.org/10.1111/jfpp.15526
Graduate Students    
Lic. Behrens Leonel Agustín
Doctoral Fellow – CONICET
Lic. Friedman Ivana Soledad
Doctoral Fellow – CONICET
Lic. Liebana Clara
Doctoral Fellow – CONICET